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姓 名:
 游书力
性 别:
 男
职 称:
 研究员
学 历:
 博士研究生
电 话:
 021-54925085
传 真:
 021-54925087
电子邮件:
 slyou@sioc.ac.cn
个人主页:
 http://shuliyou.sioc.ac.cn
通讯地址:
 上海市零陵路345号金属有机国家重点实验室 200032

简历:

* 2017年1月始:主任,中科院上海有机所金属有机国家重点实验室

* 2006年4月始:研究员,中科院上海有机所金属有机国家重点实验室

* 2004年2月-2006年4月:Principal Investigator, Genomics Institute of the Novartis Research Foundation (GNF), San Diego, CA USA

* 2001年9月-2004年1月:Postdoctoral fellow, Professor Jeffery W. Kelly, Department of Chemistry, The Scripps Research Institute, La Jolla, CA USA

* 1996年9月-2001年7月:硕博研究生,(导师:戴立信院士)中科院上海有机所


研究方向:

金属有机、不对称催化、有机合成、药物化学


专家类别:
百人;研究员;杰青

职务:
课题组长

社会任职:

获奖及荣誉:

Advisory Board, Chemical Society Reviews, 2011.1.1-
Advisory Board, Organic & Biomolecular Chemistry, 2011.1.1-
AstraZeneca Excellence in Chemistry Award (2011)
朱李月华优秀教师奖(2011)
第三届中国化学会-英国皇家化学会青年化学奖 (2011)
2007年度“百人计划”入选者终期评估为优秀(2011)
国家杰出青年科学基金(2010)
Thieme Chemistry Journals Award (2010)
中国化学会青年化学奖(2008)
第一届中美教授联合会“杰出青年教授奖” (2008)
中国化学会-约翰威立出版公司青年化学论文奖(2007)
全国百篇优秀博士论文(2003)

代表论著:

Books edited:

1.      S.-L. You (2016) Asymmetric Dearomatization Reactions, Wiley-VCH.

2.      S.-L. You (2015) Asymmetric Functionalization of C-H Bonds, Royal Society of Chemistry.

 

Publications selected-

1.        Yang, Z.-P.; Jiang, R.; Zheng, C.*; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Alkylation of Hydroxyquinolines: Simultaneous Weakening the Aromaticity of Two Consecutive Aromatic Rings. J. Am. Chem. Soc. 2018, 140, DOI: 10.1021/jacs.8b00136.

2.        Xia, Z.-L.; Zheng, C.*; Wang, S.-G.; You, S.-L.* Catalytic Asymmetric Dearomatization of Indolyl Dihydropyridines via Enamine Isomerization/Spirocyclization/Transfer Hydrogenation Sequence. Angew. Chem. Int. Ed. 2018, 57, DOI: 10.1002/anie.201712435.

3.        Cheng, Q.; Zhang, F. Cai, Y.; Guo, Y.-L.*; You, S.-L.* Stereodivergent Synthesis of Tetrahydrofuroindoles via Pd-Catalyzed Asymmetric Dearomative Formal [3+2] Cycloaddition Reactions. Angew. Chem. Int. Ed. 2018, 57, 2134-2138.

4.        Cai, Z.-J.; Liu, C.-X.; Gu, Q.; You, S.-L.* Thioketone Directed Palladium(II)-Catalyzed C-H Arylation of Ferrocenes with Aryl Boronic Acids. Angew. Chem. Int. Ed. 2018, 57, 1296-1299.

5.        Zhang, X.; You, S.-L.* Removing the Mask in Catalytic Asymmetric Diamination of Alkenes. Chem. 2017, 2, 917-929.

6.        Wang, Y.; Zheng, C.*; You, S.-L.* Ir-Catalyzed Asymmetric Allylic Dearomatization via a Desymmetrization Strategy. Angew. Chem. Int. Ed. 2017, 56, 15093-15097. (VIP)

7.        Huang, L.; Cai, Y.; Zheng, C.; Dai, L.-X.; You, S.-L.* Iridium-Catalyzed Enantioselective Synthesis of Pyrrole-Annulated Medium-Sized-Ring Compounds. Angew. Chem. Int. Ed. 2017, 56, 10545-10548.

8.        Cheng, Q.; Zhang, H.-J.; Yue, W.-J.; You, S.-L.* Palladium-Catalyzed Highly Stereoselective Dearomative [3+2] Cycloaddition of Nitrobenzofurans. Chem. 2017, 2, 428-436.

9.        Wang, S.-G.; Xia, Z.-L.; Xu, R.-Q.; Liu, X.-J.; Zheng, C.; You, S.-L.* Construction of Chiral Tetrahydro-β-Carbolines through Asymmetric Pictet-Spengler Reaction of Indolyl Dihydropyridines. Angew. Chem. Int. Ed. 2017, 56, 7440-7443. (Wang, S.-G. and Xia, Z.-L. contribute equally)

10.    Xu, R.-Q.; Gu, Q.; You, S.-L.* Construction of Benzomesembrine Skeleton via Pd(0)-Catalyzed Intermolecular Arylative Dearomatization of α-Naphthols and Aza-Michael Cascade. Angew. Chem. Int. Ed. 2017, 56, 7252-7256.

11.    Wang, J.; Gao, D.-W.; Huang, J.; Tang, S.; Xiong, Z.; Hu, H.; You, S.-L.*; Zhu, Q.* Palladium-Catalyzed Enantioselective C(sp2)–H Imidoylation by Desymmetrization. ACS Catal. 2017, 7, 3832-3836.

12.    Zheng, J.; Wang, S.-B.; Zheng, C.; You, S.-L.* Asymmetric Synthesis of Spiropyrazolones via Rh-Catalyzed C(sp2)?H Functionalization/Annulation Reactions. Angew. Chem. Int. Ed. 2017, 56, 4540-4544.

13.    Liu, X.-J.; You, S.-L.* Enantioselective Iridium-Catalyzed Allylic Substitution with 2-Methylpyridines. Angew. Chem. Int. Ed. 2017, 56, 4002-4005. Highlighted by Synfacts, Paul Knochel, Marthe Ketels, Synfacts, 2017, 0528.

14.    Gao, D.-W.; Gu, Q.; Zheng, C.; You, S.-L.* Synthesis of Planar Chiral Ferrocenes via Transition-Metal-Catalyzed Direct C–H Bond Functionalization Acc. Chem. Res. 2017, 50, 351-365.

15.    Tu, H.-F.; Zheng, C.; Xu, R.-Q.; Liu, X.-J.; You, S.-L.* Ir-Catalyzed Intermolecular Asymmetric Dearomatization of β-Naphthols with Allyl Alcohols or Allyl Ethers. Angew. Chem. Int. Ed. 2017, 56, 3237-3241. (VIP) Highlighted by Synfacts, Hisashi Yamamoto, Ramesh C. Samanta, Synfacts, 2017, 0278.

16.    Yang, Z.-P.; Zheng, C.; Huang, L.; Qian, C.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzoxazoles, Benzothiazoles and Benzimidazoles. Angew. Chem. Int. Ed. 2017, 56, 1530-1534. Highlighted by Synfacts, Hisashi Yamamoto, Yasushi Shimoda, Synfacts, 2017, 0492.

17.    Zheng, C.; You, S.-L.* Catalytic Asymmetric Dearomatization (CADA) by Transition-metal-catalysis: A Method for Transformations of Aromatic Compounds. Chem. 2016, 1, 830-857.

18.    Xu, R.-Q.; Yang, P.; Tu, H.-F.; Wang, S.-G.; You, S.-L.* Palladium(0)-Catalyzed Intermolecular Arylative Dearomatization of β-Naphthols. Angew. Chem. Int. Ed. 2016, 55, 15137-15141.

19.    Wang, D.-C.; Xie, M.-S.; Guo, H.-M.*; Qu, G.-R.; Zhang, M.-C.; You, S.-L.* Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles. Angew. Chem. Int. Ed. 2016, 55, 14111-14115. Highlighted by Synfacts, Mark Lautens, Hyung Yoon, Synfacts, 2016, 1266.

20.    Zhuo, C.-X.; Zhang, X.; You, S.-L.* Enantioselective Synthesis of Pyrrole-Fused Piperazine and Piperazinone Derivatives via Ir-Catalyzed Asymmetric Allylic Amination. ACS Catal. 2016, 6, 5307-5310. Highlighted by Synfacts, Hisashi Yamamoto, Ramesh C. Samanta, Synfacts, 2016, 1043.

21.    Huang, L.; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of Indole-Annulated Medium-Sized Rings. J. Am. Chem. Soc. 2016, 138, 5793-5796. Highlighted by C&EN.

22.    Ye, K.-Y.; Cheng, Q.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Iridium(I) N-Heterocyclic Carbene Complex Catalyzed Asymmetric Intramolecular Allylic Amination Reactions. Angew. Chem. Int. Ed. 2016, 55, 8113-8116.

23.    Zheng, J.; Cui, W.-J.; Zheng, C.; You, S.-L.* Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes. J. Am. Chem. Soc. 2016, 138, 5242-5245.

24.    Wu, Q.-F.; Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Highly Efficient Synthesis and Stereoselective Migration Reactions of Chiral Five-Membered Aza-Spiroindolenines: Scope and Mechanistic Understanding. Chem. Sci. 2016, 7, 4453-4459. Highlighted by Synfacts, Mark Lautens, Hyung Yoon, Synfacts, 2016, 0606.

25.    Gao, D.-W.; Gu, Q.; You, S.-L.* An Enantioselective Oxidative C–H/C–H Cross-Coupling Reaction: Highly Efficient Method to Prepare Planar Chiral Ferrocenes. J. Am. Chem. Soc. 2016, 138, 2544-547.

26.    Cheng, Q.; Wang, Y.; You, S.-L.* Chemo-, Diastereo- and Enantioselective Ir-Catalyzed Allylic Intramolecular Dearomatization Reaction of Naphthol Derivatives. Angew. Chem. Int. Ed. 2016, 55, 3496-3499. Highlighted by Synfacts, Hisashi Yamamoto, Masahiro Sai, Synfacts, 2016, 0489.

27.    Wu, W.-T.; Xu, R.-Q.; Zhang, L.*; You, S.-L.* Construction of Spirocarbocycles via Gold-Catalyzed Intramolecular Dearomatization of Naphthols. Chem. Sci. 2016, 7, 3427-3431.

28.    Wu, W.-T.; Zhang, L.*; You, S.-L.* Catalytic Asymmetric Dearomatization (CADA) Reactions of Phenol and Aniline Derivatives Chem. Soc. Rev. 2016, 45, 1570-1580.

29.    Zheng, C.*; Zheng, J.; You, S.-L.* A DFT Study on Rh-Catalyzed Asymmetric Dearomatization of 2-Naphthols Initiated with C–H Activation: A Refined Reaction Mechanism and Origins of Multiple Selectivity. ACS Catal. 2016, 6, 262-271.

30.    Liu, C.; Yi, J.-C.; Zheng, Z.-B.; Tang, Y.*; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of 3a-Amino-pyrroloindolines via Copper-Catalyzed Direct Asymmetric Dearomative Amination of Tryptamines. Angew. Chem. Int. Ed. 2016, 55, 751-754.

31.    Yang, Z.-P.; Wu, Q.-F.; Shao, W.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Pyridines, Pyrazines, Quinolines and Isoquinolines. J. Am. Chem. Soc. 2015, 137, 15899-15906.

32.    Wang, S.-G.; Liu, X.-J.; Zhao, Q.-C.; Zheng, C.; Wang, S.-B.; You, S.-L.* Asymmetric Dearomatization of β-Naphthols through a Bifunctional-Thiourea-Catalyzed Michael Reaction. Angew. Chem. Int. Ed. 2015, 54, 14929-14932. Highlighted by Synfacts, Benjamin List, Ti Gatzenmeier, Synfacts, 2016, 0087.

33.    Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.; You, S.-L.* Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives: Reactive Spiroindolenine Intermediates. Angew. Chem. Int. Ed. 2015, 54, 14146-14149.

34.    Zhang, X.; Liu, W.-B.; Tu, H.-F.; You, S.-L.* Ligand-Enabled Ir-Catalyzed Intermolecular Diastereoselective and Enantioselective Allylic Alkylation of 3-Substituted Indoles. Chem. Sci. 2015, 6, 4525-4529.

35.    Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L.* Enantioselective Synthesis of Pyrrole Based Spiro- and Polycyclic Derivatives by Ir-catalyzed Asymmetric Allylic Dearomatization and Controllable Migration Reactions. Angew. Chem. Int. Ed. 2015, 54, 8475-8479. Highlighted by www.organic-chemistry.org/Highlights/2016/17October.shtm (column on "heterocycles")

36.    Li, G.-T.; Gu, Q.; You, S.-L.* Enantioselective Annulation of Enals with 2-Naphthols by Triazolium Salts Derived from L-Phenylalanine. Chem. Sci. 2015, 6, 4273-4278.

37.    Yin, Q.; Wang, S.-G.; Liang, X.-W.; Gao, D.-W.; Zheng, J.; You, S.-L.* Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols. Chem. Sci. 2015, 6, 4179-4183.

38.    Shao, W.; Li, H.; Liu, C.; Liu, C.-J.*; You, S.-L.* Copper-Catalyzed Intermolecular Asymmetric Propargylic Dearomatization of Indoles. Angew. Chem. Int. Ed. 2015, 54, 7684-7687.

39.    Zheng, J.; Wang, S.-B.; Zheng, C.; You, S.-L.* Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction. J. Am. Chem. Soc. 2015, 137, 4880-4883. Highlighted by Synfacts, Mark Lautens, Thomas Johnson, Synfacts, 2015, 0721. (Synfacts of the month)

40.    Zhang, X.; Yang, Z.-P.; Huang, L.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of N-Substituted 2-pyridones via Ir-Catalyzed Intermolecular Asymmetric Allylic Amination. Angew. Chem. Int. Ed. 2015, 54, 1873-1876.

41.    Wang, S.-G.; Yin, Q.; Zhuo, C.-X.; You, S.-L.* Asymmetric Dearomatization of β-Naphthols via Chiral Phosphoric Acid-Catalyzed Amination Reaction. Angew. Chem. Int. Ed. 2015, 54, 647-650.

42.    Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Mechanistic Insights into the Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Multisubstituted Pyrroles: Understanding the Remarkable Regio- and Enantioselectivity. J. Am. Chem. Soc. 2014, 136, 16251-16259.

43.    Xu, R.-Q.; Gu, Q.; Wu, W.-T.; Zhao, Z.-A.; You, S.-L.* Construction of Erythrinane Skeleton via Pd(0)-Catalyzed Intramolecular Dearomatization of para-Aminophenols J. Am. Chem. Soc. 2014, 136, 15469-15472.

44.    Zheng, J.; You, S.-L.* Construction of Axial Chirality via Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes. Angew. Chem. Int. Ed. 2014, 53, 13244-13247.

45.    Gao, D.-W.; Gu, Q.*; You, S.-L.* Pd(II)-Catalyzed Intermolecular Direct C-H Bond Iodination: An Efficient Approach towards the Synthesis of Axially Chiral Compounds via Kinetic Resolution. ACS Catal. 2014, 4, 2741-2745.

46.    Zhuo, C.-X.; Zheng, C.; You, S.-L.* Transition-metal-catalyzed Asymmetric Allylic Dearomatization Reactions Acc. Chem. Res. 2014, 47, 2558-2573.

47.    Yang, Z.-P.; Wu, Q.-F.; You, S.-L.* Direct Asymmetric Dearomatization of Pyridines and Pyrazines via Ir-Catalyzed Allylic Amination Reactions. Angew. Chem. Int. Ed. 2014, 53, 6986-6989. Highlighted by Synfacts, Mark Lautens, Steffen Kress, Synfacts, 2014, 0819.

48.    Zhuo, C.-X.; Zhou, Y.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of Poly-Substituted 2H-Pyrroles via Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Pyrroles J. Am. Chem. Soc. 2014, 136, 6590-6593 (selected as JACS Spotlights). Highlighted by Synfacts, Mark Lautens, Zafar Qureshi, Synfacts, 2014, 0820. (http://www.organic-chemistry.org/Highlights/2014/17November.shtm)

49.    Gao, D.-W.; Yin, Q.; Gu, Q.*; You, S.-L.* Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd(0)-Catalyzed Intramolecular Direct C-H Bond Arylation J. Am. Chem. Soc. 2014, 136, 4841-4844. Highlighted by Synfacts, Mark Lautens, David A Petrone, Synfacts, 2014, 0597.

50.    Li, W.; Liu, C.; Zhang, H.; Ye, K.; Zhang, G.; Zhang, W.; Duan, Z.; You, S.*; Lei, A.* Palladium-Catalyzed Oxidative C-H/N-H Carbonylation for the Synthesis of β-lactams. Angew. Chem. Int. Ed. 2014, 53, 2443-2446. Highlighted by Synfacts, Victor Snieckus, Suneel P. Singh, Synfacts, 2014, 0360. (http://www.organic-chemistry.org/Highlights/2014/17November.shtm)

51.    Wang, S.-G.; You, S.-L.* Cascade Hydrogenative Dearomatization of Pyridine and Asymmetric aza-Friedel-Crafts Alkylation Reaction. Angew. Chem. Int. Ed. 2014, 53, 2194-2197. Highlighted by Synfacts, Benjamin List, Philip S. J. Kaib, Synfacts, 2014, 0431.

52.    Zhang, X.; Han, L.; You, S.-L.* Ir-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Indoles. Chem. Sci. 2014, 5, 1059-1063. Highlighted by Synfacts, Hisashi Yamamoto, Sukalyan Bhadra, Synfacts, 2014, 0596.

53.    Zhuo, C.-X.; You, S.-L.* Palladium-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Naphthol Derivatives. Angew. Chem. Int. Ed. 2013, 52, 10056-10059. Highlighted by Synfacts, Mark Lautens, Zafar Qureshi, Synfacts, 2013, 1308.

54.    Zhang, X.; Yang, Z.-P.; Liu, C.; You, S.-L.* Ru-Catalyzed Intermolecular Dearomatization Reaction of Indoles with Allylic Alcohols. Chem. Sci. 2013, 4, 3239-3243. Highlighted by Synfacts, Mark Lautens, Lei Zhang, Synfacts, 2013, 0960.

55.    Zhuo, C.-X.; Wu, Q.-F.; Zhao, Q.; Xu, Q.-L.; You, S.-L.* Enantioselective Functionalization of Indoles and Pyrroles via An in-situ Formed Spiro-intermediate J. Am. Chem. Soc. 2013, 135, 8169-8172. Highlighted by Synfacts, Mark Lautens, Jennifer Tsoung, Synfacts, 2013, 0874.

56.    Jia, M.-Q.; You, S.-L.* N-Heterocyclic Carbene-Catalyzed Enantioselective Intramolecular N-Tethered Aldehyde-Ketone Benzoin Reactions. ACS Catal. 2013, 3, 622-624.

57.    Gao, D.-W.; Shi, Y.-C.; Gu, Q.*; Zhao, Z.-L.; You, S.-L.* Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-catalyzed Direct Coupling with Aryl Boronic Acids J. Am. Chem. Soc. 2013, 135, 86-89. Highlighted by Synfacts, Hisashi Yamamoto, Jiajing Tan, Synfacts, 2013, 0147.

58.    Xu, Q.-L.; Dai, L.-X.; You, S.-L.* Diversity Oriented Synthesis of Indole-based Peri-annulated Compounds via Allylic Alkylation Reactions. Chem. Sci. 2013, 4, 97-102.

59.    Zhuo, C.-X.; Zhang, W.*; You, S.-L.* Catalytic Asymmetric Dearomatization Reactions. Angew. Chem. Int. Ed. 2012, 51, 12662-12686.

60.    Liu, W.-B.; Zhang, X.; Dai, L.-X.; You, S.-L.* Asymmetric N-Allylation of Indoles via Ir-Catalyzed Allylic Alkylation of Indolines and Oxidation Strategy. Angew. Chem. Int. Ed. 2012, 51, 5183-5187.

61.    Liu, W.-B.; Zheng, C.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Ir-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies J. Am. Chem. Soc. 2012, 134, 4812-4821. Highlighted by Synfacts, Mark Lautens, Hasnain A. Malik, Synfacts, 2012, 0637.

62.    Zheng, C.; You, S.-L.* Transfer Hydrogenation with Hantzsch Esters and Related Organic Hydride Donors Chem. Soc. Rev. 2012, 41, 2498-2518. (invited paper)

63.    Wu, Q.-F.; Zheng, C.; You, S.-L.* Enantioselective Syntheses of Spiro Cyclopentane-1,3'-indoles and 2,3,4,9-Tetrahydro-1H-carbazoles via Ir-Catalyzed Allylic Dearomatization and Stereospecific Migration. Angew. Chem. Int. Ed. 2012, 51, 1680-1683. Highlighted by Synfacts, Hisashi Yamamoto, Patrick Brady, Synfacts, 2012, 0529.

64.    Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L.* Asymmetric Dearomatization of Pyrroles via Ir-Catalyzed Allylic Substitution Reaction: Enantioselective Synthesis of Spiro-2H-pyrroles. Chem. Sci. 2012, 3, 205-208.

65.    Ye, K.-Y.; He, H.; Liu, W.-B.; Helmchen, G.; Dai, L-X.; You, S.-L.* Iridium-Catalyzed Allylic Vinylation and Asymmetric Allylic Amination Reactions with ortho-Aminostyrenes J. Am. Chem. Soc. 2011, 133, 19006-19014. Highlighted by Synfacts, Mark Lautens, Hongqiang Liu, Synfacts, 2012, 0170.

66.    Cai, Q.; Zheng, C.; Zhang, J.-W.; You, S.-L.* Enantioselective Michael-Mannich Polycyclization Cascade of Indolyl Enones by Quinine-Derived Primary Amine Angew. Chem. Int. Ed. 2011, 50, 8665-8669.

67.    Gu, Q.; You, S.-L.* Desymmetrization of Cyclohexadienones via Cinchonine Derived Thiourea-Catalyzed Enantioselective Aza-Michael Reaction and Total Synthesis of (-)-Mesembrine. Chem. Sci. 2011, 2, 1519-1522. Highlighted by Synfacts, Benjamin List, Qinggang Wang, Synfacts, 2011, 1242.

68.    Yin, Q.; You, S.-L.* Chiral Phosphoric Acid-Catalysed Friedel-Crafts Alkylation Reaction of Indoles with Racemic Spiro Indolin-3-ones. Chem. Sci. 2011, 2, 1344-1348.

69.    Wu, Q.-F.; Liu, W.-B.; Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.; You, S.-L.* Ir-Catalyzed Intramolecular Asymmetric Allylic Dearomatization of Phenols. Angew. Chem. Int. Ed. 2011, 50, 4455-4458. Highlighted by Synfacts, Hisashi Yamamoto, Jiajing Tan, Synfacts, 2011, 0854.

70.    Cai, Q.; Zheng, C.; You, S.-L.* Enantioselective Intramolecular Aza-Michael Addition of Indoles Catalyzed by Chiral Phosphoric Acid. Angew. Chem. Int. Ed. 2010, 49, 8666-8669. Highlighted by Synfacts, Benjamin List, Ji-Woong Li, Synfacts, 2010, 1428.

71.    Wu, Q.-F.; He, H.; Liu, W.-B.; You, S.-L.* Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation Reactions J. Am. Chem. Soc. 2010, 132, 11418-11419.

72.    Peng, H. M.; Dai, L.-X.; You, S.-L.* Enantioselective Palladium-Catalyzed Direct Alkylation and Olefination Reaction of Simple Arenes Angew. Chem. Int. Ed. 2010, 49, 5826-5828. (Highlights)

73.    Gu, Q.; Rong, Z.-Q.; Zheng, C.; You, S.-L.* Desymmetrization of Cyclohexadienones via Br?nsted Acid-Catalyzed Enantioselective Oxo-Michael Reaction J. Am. Chem. Soc. 2010, 132, 4056-4057. Highlighted by Synfacts, Benjamin List, Steffen Muller, Synfacts, 2010, 0828.

74.    He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of 2,3-Dihydro-1H-benzo[b]azepines via Ir-Catalyzed Tandem Allylic Vinylation/Amination Reaction. Angew. Chem. Int. Ed. 2010, 49, 1496-1499. Highlighted by Synfacts, Mark Lautens, Jane Panteleev, Synfacts, 2010, 0466.

75.    Cai, Q.; Zhao, Z.-A.; You, S.-L.* Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/ Intramolecular Friedel-Crafts Alkylation under Sequential Catalysis. Angew. Chem. Int. Ed. 2009, 48, 7428-7431. Highlighted by Synfacts, Mark Lautens, Jacki Kitching, Synfacts, 2009, 1375.

76.    He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L.* Ir-Catalyzed Cross-Coupling of Styrene Derivatives with Allylic Carbonates: Free Amine Assisted Vinyl C-H Bond Activation J. Am. Chem. Soc. 2009, 131, 8346-8347. Highlighted by Synfacts, Mark Lautens, Jacki Kitching, Synfacts, 2009, 0987.

77.    You, S.-L.*; Cai, Q.; Zeng, M. Chiral Br?nsted Acids Catalyzed Friedel-Crafts Alkylation Reaction Chem. Soc. Rev. 2009, 38, 2190-2201. (invited paper)

78.    Kang, Q.; Zhao, Z.-A.; You, S.-L.* Highly Enantioselective Friedel-Crafts Reaction of Indoles with Imines by a Chiral Phosphoric Acid. J. Am. Chem. Soc. 2007, 129, 1484-1485. (a Most-Accessed Article for the first-quarter of 2007) Highlighted by Synfacts, Victor Snieckus, Wei Gan, Synfacts, 2007, 0471. & Benjamin List, Subhas Chandra Pan, Synfacts, 2007, 0547.

79.    You, S.-L.*; Dai, L.-X. Enantioselective Palladium-Catalyzed Decarboxylative Allylic Alkylations. Angew. Chem. Int. Ed. 2006, 45, 5246-5248.

 

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