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您的位置: 首页>研究队伍>人才
姓 名:
 汤文军
性 别:
 男
职 称:
 研究员
学 历:
 博士研究生
电 话:
 021-54925515
传 真:
 021-64166128
电子邮件:
 tangwenjun@sioc.ac.cn
个人主页:
 http://wenjuntang.sioc.ac.cn
通讯地址:
 上海市零陵路345号 200032

简历:

1974年10月出生于浙江余姚;1995年毕业于华东理工大学精细化工系;1998年于中国科学院上海有机化学研究所获硕士学位;2003年于美国宾夕法尼亚州立大学获博士学位;2003-2005 年在美国Scripps 研究所从事博士后研究;2005-2009年在美国Boehringer Ingelheim 药业公司药物工艺部门(Chemical Development) 任高级科学家(Senior Scientist), 在2009-2011年间任首席科学家 (Principal Scientist);2011年7月起任中科院上海有机化学研究所研究员、课题组长;2012年2月入选第七批国家“千人计划(青年项目)”


研究方向:

发展新型高效的不对称催化反应; 对具有重要生理活性的复杂天然产物的全合成;发展高效,经济,绿色的药物新工艺.


专家类别:
研究员;千人计划

职务:
课题组长

社会任职:

获奖及荣誉:
2013年入选上海“浦江人才”计划
2012年入选第七批国家“千人计划(青年项目)”
2012年获Thieme Journal Award
2009年获美国Boehringer Ingelheim 药业公司President’s Award for Individual Excellence
2001-2003获美国宾夕法尼亚州立大学Dalalian Major Fellowship
代表论著:

1.Guangqing Xu, Wenzhen Fu, Guodu Liu, Chris H. Senanayake, Wenjun Tang* Efficient Syntheses of Korupensamine A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions J. Am. Chem. Soc. DOI: 10.1021/ja409669r
2. Guodu Liu, Guangqing Xu, Renshi Luo, Wenjun Tang* “Search for Ideal P-Chiral Phosphorus Ligands for Practical Asymmetric Hydrogenation and Asymmetric Suzuki-Miyaura Coupling” Synlett 2013, 24, 2465-2471 (Synpacts).
3.Renshi Luo, Ke Li, Yuling Hu, Wenjun Tang* “Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Trifluoromethyl Ketones” Adv. Syn. Cat. 2013, 355, 1297-1302
4.Guodu Liu, Xiangqian Liu, Zhihua Cai, Guangjun Jiao, Guangqing Xu, Wenjun Tang* Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis fo Chiral β-Arylamines by Asymmetric Hydrogenation Angew. Chem., Int. Ed. 2013, 52, 4235-4238
5. Qing Zhao, Chengxi Li, Chris H. Senanayake, Wenjun Tang* “An Efficient Method for Sterically Demanding Suzuki-Miyaura Coupling Reactions” Chem. Eur. J., 2013, 19, 2261
6.Wenjun Tang,* Nitinchandra D. Patel, Guangqing Xu, Xiaobing Xu “Efficient Chiral Monophosphorus Ligands for Asymmetric Suzuki–Miyaura Coupling ReactionsOrg. Lett. 2012, 14 , 2258–2261
7. Wenjun Tang,* Xudong Wei, Nathan K. Yee, Nitinchandra Patel, Heewon Lee, and Chris H. Senanayake, A Practical Asymmetric Synthesis of Isopropyl (1R,2S)-Dehydrocoronamate Org. Process Res. Dev. 2011, 15, 1207-1211
8.Wenjun Tang,* Santosh Keshipeddy,Yongda Zhang, Xudong Wei, Jolaine Savoie, Nitinchandra D. Patel, Nathan K. Yee, and Chris H. Senanayake Efficient Monophosphorus Ligands for Palladium-Catalyzed Miyaura Borylation Org. Lett. 2011, 13, 1366-1369.
9.Sonia Rodriguez,* Bo Qu, Nizar Haddad, Diana Reeves, Wenjun Tang,* Dhileepkumar Krishnamurthy and Chris H. Senanayake Dihydrobenzooxaphosphole-Based Monophosphorus Ligands for Palladium-Catalyzed Amination Reactions Adv. Asy. Cat. 2011, 353, 533-537
10.Wenjun Tang,* Andrew G. Capacci, Xudong Wei, Wenjie Li, Andre White, Nitinchandra D. Patel, Jolaine Savoie, Joe J. Gao, Sonia Rodriguez, Bo Qu, Nizar Haddad, Bruce Z. Lu, Dhileepkumar Krishnamurthy, Nathan K. Yee and Chris  H. Senanayake A General and Special Catalyst for Suzuki-Miyaura Coupling Processes Angew. Chem., Int. Ed. 2010, 49, 5879-5883.
11. Wenjun Tang,* Andrew G. Capacci, Andre White, Shengli Ma, Sonia Rodriguez, Bo Qu, Jolaine Savoie, Nitinchandra Patel, Xudong Wei, Nizar Haddad, Nelu Grinberg, Nathan K. Yee, Dhileep Krishnamurthy, and Chris H. Senanayake Novel and Efficient Chiral Bisphosphorus Ligands for Rhodium-Catalyzed Asymmetric Hydrogenation” Org. Lett. 2010, 12, 1104-1107.
12. Wenjun Tang,* Bo Qu, Andrew Capacci, Sonia Rodriguez, Xudong Wei, Nizar Haddad, Bikashandarkoil Narayanan, Shengli Ma, Nelu Grinberg, Nathan K. Yee, and Chris H. Senanayake Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation, Org. Lett. 2010, 12, 176-179.
13.Wenjun Tang,* Andrew Capacci, Max Sarvestani, Xudong Wei, Nathan K. Yee, and Chris H. Senanayake A Facile and Practical Synthesis of N-Acetyl Enamides J. Org. Chem. 2009, 74, 9528-9530.
14.K. C. Nicolaou,* Theocharis V. Koftis, Stepan Vyskocil, Goran Petrovic, Wenjun Tang, Michael O. Frederick, David Y.-K. Chen, Yiwei Li, Taotao Ling, and Yoichi M. A. Yamada, “Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1,” J. Am. Chem. Soc. 2006, 128, 2859-2872.
15.K. C. Nicolaou,* Wenjun Tang, Philippe Dagneau, and Raffaella Faraoni A catalytic asymmetric three-component 1,4-addition/aldol reaction: Enantioselective synthesis of the spirocyclic system of vannusal A  Angew. Chem., Int. Ed. 2005, 44, 3874-3879.
16.K. C. Nicolaou,* Theocharis V. Koftis, Stepan Vyskocil, Goran Petrovic, Taotao Ling, Yoichi M. A. Yamada, Wenjun Tang, and Michael O. Frederick Structural revision and total synthesis of Azaspiracid-1, part 2: Definition of the ABCD domain and total synthesis Angew. Chem., Int. Ed. 2004, 43, 4312-4318.
17.Wenjun Tang, Shulin Wu, and Xumu Zhang,* Enantioselective hydrogenation of tetrasubstituted olefines of cyclic b-(acylamino) acrylates J. Am. Chem. Soc. 2003, 125, 9570-9571.
18.Wenjun Tang, Weimin Wang, Yongxiang Chi, and Xumu Zhang,* A P-chiral-bisphosphepine ligand for practical synthesis of β-aryl β-amino acids via asymmetric hydrogenation Angew. Chem., Int. Ed. 2003, 42, 3509-3511.
19.Wenjun Tang, and Xumu Zhang,* New chiral phosphorous ligands for enantioselective hydrogenation Chem. Rev. 2003, 103, 3029-3069.
20.Wenjun Tang, Weimin Wang, and Xumu Zhang,* A new class of phospholane-oxazoline ligands for Ir-catalyzed asymmetric hydrogenation Angew. Chem., Int. Ed. 2003, 42, 943-946.
21.Wenjun Tang, and Xumu Zhang,* A chiral 1,2-bisphospholane ligand with a novel structural motif: Applications in highly enantioselective Rh-catalyzed hydrogenations Angew. Chem., Int. Ed. 2002, 41, 1612-1614. 

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