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姓 名:
 王若文
性 别:
 男
职 称:
 副研究员
学 历:
 博士研究生
电 话:
 021-54925186
传 真:
 021-64166128
电子邮件:
 wangrw@mail.sioc.ac.cn
个人主页:
 
通讯地址:
 上海市零陵路345号 200032

简历:
2011年7月始:副研究员,中科院上海有机化学研究所有机氟化学重点实验室卿凤翎研究员课题组
2009年5月-2011年4月:博士后研究助理,佛罗里达大学化学系,Professor Weihong Tan
2006年9月-2009年4月:博士后研究助理,匹兹堡大学药学院,Professor Barry Gold
2003年9月-2006年7月:博士研究生,(导师:卿凤翎研究员)中科院上海有机所

研究方向:
含氟药物与活性生物分子的合成以及合成方法学研究

专家类别:
副研究员

职务:

社会任职:

获奖及荣誉:
代表论著:

(11) Quan Yuan, Yunfei Zhang, Ruowen Wang, Chaolin Du, Yasun Emir, and Weihong Tan. ‘DNA Using Silver Nanowire Antennas to Enhance the Conversion Efficiency of Photoresponsive DNA Nanomotors’; PNAS, 2011, 108, 9331.
(10) Ming-Xu You, Zhi Zhu, Hai-Peng Liu, Basri Gulbakan, Da Han, Ruo-Wen Wang, Kathryn R. Williams, and Weihong Tan.* ‘Pyrene-Assisted Efficient Photolysis of Disulfide Bonds in DNA-Based Molecular Engineering’; ACS Applied Materials & Interfaces, 2010, 2, 3601.
(9) Yanrong Wu, Kwame Sefaha, Haipeng Liu, Ruowen Wang, and Weihong Tan. ‘DNA aptamer–micelle as an efficient detection/delivery vehicle toward cancer cells’; PNAS, 2010, 107, 5-10.
(8) Barry Gold, Ruo-Wen Wang. “Synthetic Method to Prepare Guanine and 7-Deazaguanine Nucleosides.” US Patent Application.
(7) Manjori Ganguly, Ruo-Wen Wang, Luis A. Marky and Barry Gold.* ‘Introduction of Cationic Charge into DNA Near the Major Groove Edge of a Guanine•Cytosine Base Pair: Characterization of Oligodeoxynucleotides Substituted with 7-Aminometh yl-7-deaza-2′-deoxyguanosine’; J. Am. Chem. Soc., 2009, 131, 12068–12069
(6) Ruo-Wen Wang and Barry Gold *; “A Facile Synthetic Approach to 7-Deazaguan-ine Nucleosides via a Boc Protection Strategy”; Org. Lett., 2009, 11, 2465–2468.
 (5) Ruijie Li, Mikael Bols, Cyril Rousseau, Xingang Zhang, Ruo-wen Wang and Feng-Ling Qing*; “Synthesis and Biological Evaluation of Potent Glycosidase Inhibitors: 4-Deoxy-4,4- Difluoroisofagomineand Analogues”; Tetrahedron, 2009, 65, 3717.
 (4) Ruo-Wen Wang, Jun Xu , Oscar Lopez , Mikael Bols, Feng-Ling Qing. * ‘Difluoromethylenated polyhydroxylated pyrrolidines: facile synthesis, crystal structure and biological evaluation’; Future Medicinal Chemistry, 2009, 1, 991-997.
 (3) Ruo-Wen Wang, Xiao-Long Qiu, Mikael Bols, Fernando Ortega Caballero and Feng-Ling Qing.* “Synthesis and Biological Evaluation of Glycosidase Inhibitors:gem-Difluoro- methylenated Nojirimycin Analogues”; J. Med.Chem. 2006; 49, 2989.
(2) Ruo-Wen Wang and Feng-Ling Qing*; “Highly Stereocontrolled Synthesis of gem- Difluoromethylenated Azasugars: D- and L-1,4,6-Trideoxy-4,4-difluoronojirimycin” Org. Lett., 2005, 7, 2189-2192
(1) Xiaoyu Huang*, Ruowen Wang, Pinqiao Zhao, Guolin Lu, Sen Zhang and Feng-ling Qing*; “Synthesis and Characterization of Novel Fluoropolymers Containing Sulfonyl and Perfluorocyclobutyl Units”; Polymer, 2005, 46, 7590-7597.

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