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姓 名:
 康经武
性 别:
 男
职 称:
 研究员
学 历:
 博士研究生
电 话:
 021-54925385
传 真:
 021-64166128
电子邮件:
 jingwu.kang@sioc.ac.cn
个人主页:
 
通讯地址:
 上海市零陵路345号 200032

简历:

  1986.09-1990.06  陕西师范大学化学系,学士学位

  1990.09-1996.12  中科院兰州化学物理研究所,分析化学硕士和博士学位

  1996.12-1999.05  中科院兰州化学物理研究所,博士后,助理研究员

  1999.06-2000.10  比利时鲁汶大学药学院博士后

  2000.10-2003.09  德国图宾根大学有机化学研究所事博士后

  2003.09-至今     中科院上海有机化学研究所,研究员,课题组长


研究方向:

生物分析与药物分析化学

  我们课题组通过发展分析化学新技术和新方法帮助解决生命科学和药物研发中的重要科学问题。运用分析技术,如液相色谱、亲和色谱、毛细管电泳、质谱以及手性分离等解决药物筛选,药物靶标谱的鉴定以及蛋白糖基化修饰位点和糖链结构与功能分析方面的关键问题。这些问题的解决需要复杂体系的分离分析,涉及从有机小分子的结构和含量分析到生物大分子的结构与功能分析等分析化学技术和方法。 


专家类别:
研究员

职务:
课题组长

社会任职:

获奖及荣誉:
代表论著:

  [1] F. Li, Y. Zhang, D. Qiu, J. Kang, Screening of epidermal growth factor receptor inhibitors in natural products by capillary electrophoresis combined with high performance liquid chromatography-tandem mass spectrometry, J Chromatogr A, 1400 (2015) 117-123. 

  [2] Y. Zhang, F. Li, M. Li, J. Kang, Screening of mammalian target of rapamycin inhibitors in natural product extracts by capillary electrophoresis in combination with high performance liquid chromatography–tandem mass spectrometry, J Chromatogr A, 1388 (2015) 267-273. 

  [3] T. Wang, Q. Zhang, Y. Zhang, J. Kang, Screening of protein kinase inhibitors in natural extracts by capillary electrophoresis combined with liquid chromatography–tandem mass spectrometry, J Chromatogr A, 1337 (2014) 188-193. 

  [4] X. Zhang, T. Wang, H. Zhang, B. Han, L. Wang, J. Kang, Profiling of drug binding proteins by monolithic affinity chromatography in combination with liquid chromatography–tandem mass spectrometry, J Chromatogr A, 1359 (2014) 84-90. 

  [5] Q. Zhang, X. Chen, Z. Zhu, X. Zhan, Y. Wu, L. Song, J. Kang, Structural Analysis of Low Molecular Weight Heparin by Ultraperformance Size Exclusion Chromatography/Time of Flight Mass Spectrometry and Capillary Zone Electrophoresis, Anal Chem, 85 (2013) 1819-1827. 

  [6] C. Liu, J. Kang, Improved capillary electrophoresis frontal analysis by dynamically coating the capillary with polyelectrolyte multilayers, J Chromatogr A, 1238 (2012) 146-151. 

  [7] Z. Wang, C. Liu, J. Kang, A highly sensitive method for enantioseparation of fenoprofen and amino acid derivatives by capillary electrophoresis with on-line sample preconcentration, J Chromatogr A, 1218 (2011) 1775-1779. 

  [8] Z.M. Tang, Z.Y. Wang, J.W. Kang, Screening of acetylcholinesterase inhibitors in natural extracts by CE with electrophoretically mediated microanalysis technique, Electrophoresis, 28 (2007) 360-365. 

  [9] Z.-m. Tang, J.-w. Kang, Enzyme Inhibitor Screening by Capillary Electrophoresis with an on-Column Immobilized Enzyme Microreactor Created by an Ionic Binding Technique, Anal Chem, 78 (2006) 2514-2520. 

  [10] Z. Wang, Z. Tang, Z. Gu, Z. Hu, S. Ma, J. Kang, Enantioseparation of chiral allenic acids by micellar electrokinetic chromatography with cyclodextrins as chiral selector, Electrophoresis, 26 (2005) 1001-1006. 

  [11] J. Kang, D. Bischoff, Z. Jiang, B. Bister, R.D. Suessmuth, V. Schurig, A Mechanistic study of enantiomeric separation with vancomycin and balhimycin as chiral selectors by capillary electrophoresis. dimerization and enantioselectivity, Anal Chem, 76 (2004) 2387-2392. 

  [12] J. Kang, D. Wistuba, V. Schurig, A silica monolithic column prepared by the sol-gel process for enantiomeric separation by capillary electrochromatography, Electrophoresis, 23 (2002) 1116-1120. 

  [13] J.W. Kang, A. Van Schepdael, J.A. Orwa, E. Roets, J. Hoogmartens, Analysis of polymyxin B sulfate by capillary zone electrophoresis with cyclodextrin as additive Method development and validation, J Chromatogr A, 879 (2000) 211-218. 

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