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姓 名:
 游书力
性 别:
 男
职 称:
 研究员
学 历:
 博士研究生
电 话:
 021-54925085
传 真:
 021-54925087
电子邮件:
 slyou@sioc.ac.cn
个人主页:
 http://shuliyou.sioc.ac.cn
通讯地址:
 上海市零陵路345号 200032

简历:

2017年1月始:主任,中科院上海有机所金属有机国家重点实验室

20064月始:研究员,中科院上海有机所金属有机国家重点实验室

20042-20064月:Principal Investigator, Genomics Institute of the Novartis Research Foundation (GNF), San Diego, CA USA

20019-20041月:Postdoctoral fellow (Advisor: Professor Jeffery W. Kelly), The Scripps Research Institute, La Jolla, CA USA

19969-20017月:硕博研究生 (导师:戴立信院士),中科院上海有机所

19929-19967月:本科学生,南开大学化学系


研究方向:

不对称催化、金属有机

绿色化学导向的新反应方法和技术

药物化学导向的新反应方法和技术


专家类别:
研究员

职务:
课题组长

社会任职:

获奖及荣誉:

2019 年度科学探索奖

2017/2018 Novartis Chemistry Lectureship

2017年度国家自然科学奖二等奖(第一完成人)

2016年度上海市自然科学奖二等奖(第一完成人)

2016年度何梁何利基金青年创新奖

第十四届中国青年科技奖 (2016)

2015年英国皇家化学会默克奖

2011年阿斯利康杰出化学奖

代表论著:

1.         S.-L. You (2016) Asymmetric Dearomatization Reactions, Wiley-VCH.

2.         S.-L. You (2015) Asymmetric Functionalization of C-H Bonds, Royal Society of Chemistry.

3.         Zhang, X.; You, S.-L.* Asymmetric Allylic Substitution Reactions by Ir-Catalysts Derived from C(sp2)-H Activation of Chiral Ligands. Aldrichimica ACTA. 2020, 53, 11-18.

4.         Xia, Z.-L.; Xuxu, Q.-F.; Zheng, C.*; You, S.-L.* Chiral phosphoric acid-catalyzed asymmetric dearomatization reactions. Chem. Soc. Rev. 2020, 49, 286-300.

5.         Liu, X.-J.; Jin, S.; Zhang, W.-Y.; Liu, Q.-Q.; Zheng, C.; You, S.-L.* Sequence-Dependent Stereodivergent Allylic Alkylation/Fluorination Reaction of Acyclic Ketones. Angew. Chem. Int. Ed. 2020, 59, 2039-2043 (VIP).

6.         Cheng, Y.-Z.; Zhao, Q.-R.; Zhang, X.*; You, S.-L.* Asymmetric Dearomatization of Indole Derivatives with N-Hydroxycarbamates Enabled by Photoredox Catalysis. Angew. Chem. Int. Ed. 2019, 58, 18069-18074.

7.         Cai, Z.-J.; Liu, C.-X.; Wang, Q.; Gu, Q.*; You, S.-L.* Thioketone-Directed Rhodium(I) Catalyzed Enantioselective C-H Bond Arylation of Ferrocenes. Nat. Commun. 2019, 10, 4168.

8.         Xia, Z.-L.; Zheng, C.*; Xu, R.-Q.; You, S.-L.* Chiral Phosphoric Acid Catalyzed Aminative Dearomatization of α-Naphthols/Michael Addition Sequence. Nat. Commun. 2019, 10, 3150.

9.         Wang, Q.; Cai, Z.-J.; Liu, C.-X.; Gu, Q.; You, S.-L.* Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls. J. Am. Chem. Soc. 2019, 141, 9504-9510.

10.     Liu, X.-J.; Zheng, C.; Yang, Y.-H.; Jin, S.; You, S.-L.* Iridium-Catalyzed Asymmetric Allylic Aromatization Reaction. Angew. Chem. Int. Ed. 2019, 58, 10493-10499.

11.     Cheng, Q.; Xie, J.-H.; Weng, Y.-C.; You, S.-L.* Pd-Catalyzed Dearomatization of Anthranils with Vinylcyclopropanes via [4+3] Cyclization Reaction. Angew. Chem. Int. Ed. 2019, 58, 5739-5743 (hot article).

12.     Zheng, C.*; You, S.-L.* Catalytic asymmetric dearomatization (CADA) reaction enabled total syntheses of indole-based natural products. Nat. Prod. Rep. 2019, 36, 1589-1605.

13.     Wang, Y.; Zhang, W.-Y.; You, S.-L.* Ketones and Aldehydes as O-Nucleophiles in Iridium-Catalyzed Intramolecular Asymmetric Allylic Substitution Reaction. J. Am. Chem. Soc. 2019, 141, 2228-2232.

14.     Zhu, M.; Zheng, C.*; Zhang, X.*; You, S.-L.* Synthesis of Cyclobutane-Fused Angular Tetracyclic Spiroindolines via Visible-Light-Promoted Intramolecular Dearomatization of Indole Derivatives. J. Am. Chem. Soc. 2019, 141, 2636-2644.

15.     Cai, Z.-J.; Liu, C.-X.; Gu, Q.*; Zheng C.; You, S.-L.* Pd(II)-Catalyzed Regio- and Enantioselective Oxidative C-H/C-H Cross-Coupling Reaction between Ferrocenes and Azoles. Angew. Chem. Int. Ed. 2019, 58, 2149-2153.

16.     Xia, Z.-L.; Zheng, C.*; Liang, X.-W.; Cai, Y.; You, S.-L.* Manipulation of Spiroindolenine Intermediates for the Enantioselective Synthesis of 3-(Indol-3-yl)pyrrolidines. Angew. Chem. Int. Ed. 2019, 58, 1158-1162.

17.     Cheng, Q.; Hu, H.-F.; Zheng, C.; Qu, J.-P.; Helmchen, G.*; You, S.-L.* Iridium-Catalyzed Asymmetric Allylic Substitution Reactions. Chem. Rev. 2019, 119, 1855-1969.

18.     Huang, L.; Cai, Y.; Zhang, H.-J.; Zheng, C.; Dai, L.-X.; You, S.-L.* Chemoselective N-H Functionalization of Indole Derivatives via Reissert-type Reaction Catalyzed by Chiral Phosphoric Acid. CCS Chem. 2019, 1, 106-116.

19.     Wang, Q.; Gu, Q.; You, S.-L.* Enantioselective Carbonyl Catalysis Enabled by Chiral Aldehydes. Angew. Chem. Int. Ed. 2019, 58, 6818-6825.

20.     Zhang, M.-C.; Wang, D.-C.; Xie, M.-S.; Qu, G.-R.; Guo, H.-M.*; You, S.-L.* Cu-catalyzed Asymmetric Dearomative [3+2] Cycloaddition Reaction of Benzazoles with Aminocyclopropanes. Chem. 2019, 5, 156-167.

21.     Yang, Z.-P.; Jiang, R.; Wu, Q.-F.; Huang, L.; Zheng, C.*; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzene Derivatives. Angew. Chem. Int. Ed. 2018, 57, 16190-16193.

22.     Xu-Xu, Q.-F.; Liu, Q.-Q.; Zhang, X.*; You, S.-L.* Copper-Catalyzed Ring Opening of Benzofurans and Enantioselective Hydroamination Cascade. Angew. Chem. Int. Ed. 2018, 57, 15204-15208.

23.     Tu, H.-F.; Zhang, X.; Zheng, C.; Zhu, M.; You, S.-L.* Enantioselective dearomative prenylation of indole derivatives. Nature Catal. 2018, 1, 601-608. (Tu, H.-F. and Zhang, X. contribute equally)

24.     Zheng, C.*; Xia, Z.-L.; You, S.-L.* Unified Mechanistic Understandings of Pictet–Spengler Reactions. Chem. 2018, 4, 1952-1966.

25.     Tang, S.-B.; Zhang, X.; Tu, H.-F.; You, S.-L.* Regio- and Enantioselective Rhodium-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with 1,3-Diketones. J. Am. Chem. Soc. 2018, 140, 7737-7742.

26.     Cheng, R.; Li, B.; Wu, J.; Zheng, J.; Qiu, Z.*; Tang, W.; You, S.-L.; Tang, Y.; Xie, Z.* Enantioselective Synthesis of Chiral-at-Cage o-Carboranes via Pd-Catalyzed Asymmetric B?H Substitution. J. Am. Chem. Soc. 2018, 140, 4508-4511.

27.     Yang, Z.-P.; Jiang, R.; Zheng, C.*; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Alkylation of Hydroxyquinolines: Simultaneous Weakening the Aromaticity of Two Consecutive Aromatic Rings. J. Am. Chem. Soc. 2018, 140, 3114-3119.

28.     Xia, Z.-L.; Zheng, C.*; Wang, S.-G.; You, S.-L.* Catalytic Asymmetric Dearomatization of Indolyl Dihydropyridines via Enamine Isomerization/Spirocyclization/Transfer Hydrogenation Sequence. Angew. Chem. Int. Ed. 2018, 57, 2653-2656.

29.     Cheng, Q.; Zhang, F. Cai, Y.; Guo, Y.-L.*; You, S.-L.* Stereodivergent Synthesis of Tetrahydrofuroindoles via Pd-Catalyzed Asymmetric Dearomative Formal [3+2] Cycloaddition Reactions. Angew. Chem. Int. Ed. 2018, 57, 2134-2138.

30.     Cai, Z.-J.; Liu, C.-X.; Gu, Q.; You, S.-L.* Thioketone Directed Palladium(II)-Catalyzed C-H Arylation of Ferrocenes with Aryl Boronic Acids. Angew. Chem. Int. Ed. 2018, 57, 1296-1299.

31.     Zhang, X.; You, S.-L.* Removing the Mask in Catalytic Asymmetric Diamination of Alkenes. Chem. 2017, 2, 917-929.

32.     Wang, Y.; Zheng, C.*; You, S.-L.* Ir-Catalyzed Asymmetric Allylic Dearomatization via a Desymmetrization Strategy. Angew. Chem. Int. Ed. 2017, 56, 15093-15097. (VIP)

33.     Huang, L.; Cai, Y.; Zheng, C.; Dai, L.-X.; You, S.-L.* Iridium-Catalyzed Enantioselective Synthesis of Pyrrole-Annulated Medium-Sized-Ring Compounds. Angew. Chem. Int. Ed. 2017, 56, 10545-10548.

34.     Cheng, Q.; Zhang, H.-J.; Yue, W.-J.; You, S.-L.* Palladium-Catalyzed Highly Stereoselective Dearomative [3+2] Cycloaddition of Nitrobenzofurans. Chem. 2017, 2, 428-436.

35.     Wang, S.-G.; Xia, Z.-L.; Xu, R.-Q.; Liu, X.-J.; Zheng, C.; You, S.-L.* Construction of Chiral Tetrahydro-β-Carbolines through Asymmetric Pictet-Spengler Reaction of Indolyl Dihydropyridines. Angew. Chem. Int. Ed. 2017, 56, 7440-7443. (Wang, S.-G. and Xia, Z.-L. contribute equally)

36.     Xu, R.-Q.; Gu, Q.; You, S.-L.* Construction of Benzomesembrine Skeleton via Pd(0)-Catalyzed Intermolecular Arylative Dearomatization of α-Naphthols and Aza-Michael Cascade. Angew. Chem. Int. Ed. 2017, 56, 7252-7256.

37.     Zheng, J.; Wang, S.-B.; Zheng, C.; You, S.-L.* Asymmetric Synthesis of Spiropyrazolones via Rh-Catalyzed C(sp2)?H Functionalization/Annulation Reactions. Angew. Chem. Int. Ed. 2017, 56, 4540-4544.

38.     Liu, X.-J.; You, S.-L.* Enantioselective Iridium-Catalyzed Allylic Substitution with 2-Methylpyridines. Angew. Chem. Int. Ed. 2017, 56, 4002-4005.

39.     Gao, D.-W.; Gu, Q.; Zheng, C.; You, S.-L.* Synthesis of Planar Chiral Ferrocenes via Transition-Metal-Catalyzed Direct C–H Bond Functionalization. Acc. Chem. Res. 2017, 50, 351-365.

40.     Tu, H.-F.; Zheng, C.; Xu, R.-Q.; Liu, X.-J.; You, S.-L.* Ir-Catalyzed Intermolecular Asymmetric Dearomatization of β-Naphthols with Allyl Alcohols or Allyl Ethers. Angew. Chem. Int. Ed. 2017, 56, 3237-3241. (VIP)

41.     Yang, Z.-P.; Zheng, C.; Huang, L.; Qian, C.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzoxazoles, Benzothiazoles and Benzimidazoles. Angew. Chem. Int. Ed. 2017, 56, 1530-1534.

42.     Zheng, C.; You, S.-L.* Catalytic Asymmetric Dearomatization (CADA) by Transition-metal-catalysis: A Method for Transformations of Aromatic Compounds. Chem. 2016, 1, 830-857.

43.     Xu, R.-Q.; Yang, P.; Tu, H.-F.; Wang, S.-G.; You, S.-L.* Palladium(0)-Catalyzed Intermolecular Arylative Dearomatization of β-Naphthols. Angew. Chem. Int. Ed. 2016, 55, 15137-15141.

44.     Wang, D.-C.; Xie, M.-S.; Guo, H.-M.*; Qu, G.-R.; Zhang, M.-C.; You, S.-L.* Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles. Angew. Chem. Int. Ed. 2016, 55, 14111-14115.

45.     Huang, L.; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of Indole-Annulated Medium-Sized Rings. J. Am. Chem. Soc. 2016, 138, 5793-5796.

46.     Ye, K.-Y.; Cheng, Q.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Iridium(I) N-Heterocyclic Carbene Complex Catalyzed Asymmetric Intramolecular Allylic Amination Reactions. Angew. Chem. Int. Ed. 2016, 55, 8113-8116.

47.     Zheng, J.; Cui, W.-J.; Zheng, C.; You, S.-L.* Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes. J. Am. Chem. Soc. 2016, 138, 5242-5245.

48.     Wu, Q.-F.; Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Highly Efficient Synthesis and Stereoselective Migration Reactions of Chiral Five-Membered Aza-Spiroindolenines: Scope and Mechanistic Understanding. Chem. Sci. 2016, 7, 4453-4459.

49.     Gao, D.-W.; Gu, Q.; You, S.-L.* An Enantioselective Oxidative C–H/C–H Cross-Coupling Reaction: Highly Efficient Method to Prepare Planar Chiral Ferrocenes. J. Am. Chem. Soc. 2016, 138, 2544-2547.

50.     Cheng, Q.; Wang, Y.; You, S.-L.* Chemo-, Diastereo- and Enantioselective Ir-Catalyzed Allylic Intramolecular Dearomatization Reaction of Naphthol Derivatives. Angew. Chem. Int. Ed. 2016, 55, 3496-3499.

51.     Wu, W.-T.; Xu, R.-Q.; Zhang, L.*; You, S.-L.* Construction of Spirocarbocycles via Gold-Catalyzed Intramolecular Dearomatization of Naphthols. Chem. Sci. 2016, 7, 3427-3431.

52.     Wu, W.-T.; Zhang, L.*; You, S.-L.* Catalytic Asymmetric Dearomatization (CADA) Reactions of Phenol and Aniline Derivatives Chem. Soc. Rev. 2016, 45, 1570-1580.

53.     Liu, C.; Yi, J.-C.; Zheng, Z.-B.; Tang, Y.*; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of 3a-Amino-pyrroloindolines via Copper-Catalyzed Direct Asymmetric Dearomative Amination of Tryptamines. Angew. Chem. Int. Ed. 2016, 55, 751-754.

54.     Yang, Z.-P.; Wu, Q.-F.; Shao, W.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Pyridines, Pyrazines, Quinolines and Isoquinolines. J. Am. Chem. Soc. 2015, 137, 15899-15906.

55.     Wang, S.-G.; Liu, X.-J.; Zhao, Q.-C.; Zheng, C.; Wang, S.-B.; You, S.-L.* Asymmetric Dearomatization of β-Naphthols through a Bifunctional-Thiourea-Catalyzed Michael Reaction. Angew. Chem. Int. Ed. 2015, 54, 14929-14932.

56.     Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.; You, S.-L.* Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives: Reactive Spiroindolenine Intermediates. Angew. Chem. Int. Ed. 2015, 54, 14146-14149.

57.     Zhang, X.; Liu, W.-B.; Tu, H.-F.; You, S.-L.* Ligand-Enabled Ir-Catalyzed Intermolecular Diastereoselective and Enantioselective Allylic Alkylation of 3-Substituted Indoles. Chem. Sci. 2015, 6, 4525-4529.

58.     Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L.* Enantioselective Synthesis of Pyrrole Based Spiro- and Polycyclic Derivatives by Ir-catalyzed Asymmetric Allylic Dearomatization and Controllable Migration Reactions. Angew. Chem. Int. Ed. 2015, 54, 8475-8479.

59.     Li, G.-T.; Gu, Q.; You, S.-L.* Enantioselective Annulation of Enals with 2-Naphthols by Triazolium Salts Derived from L-Phenylalanine. Chem. Sci. 2015, 6, 4273-4278.

60.     Yin, Q.; Wang, S.-G.; Liang, X.-W.; Gao, D.-W.; Zheng, J.; You, S.-L.* Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols. Chem. Sci. 2015, 6, 4179-4183.

61.     Shao, W.; Li, H.; Liu, C.; Liu, C.-J.*; You, S.-L.* Copper-Catalyzed Intermolecular Asymmetric Propargylic Dearomatization of Indoles. Angew. Chem. Int. Ed. 2015, 54, 7684-7687.

62.     Zheng, J.; Wang, S.-B.; Zheng, C.; You, S.-L.* Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction. J. Am. Chem. Soc. 2015, 137, 4880-4883.

63.     Zhang, X.; Yang, Z.-P.; Huang, L.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of N-Substituted 2-pyridones via Ir-Catalyzed Intermolecular Asymmetric Allylic Amination. Angew. Chem. Int. Ed. 2015, 54, 1873-1876.

64.     Wang, S.-G.; Yin, Q.; Zhuo, C.-X.; You, S.-L.* Asymmetric Dearomatization of β-Naphthols via Chiral Phosphoric Acid-Catalyzed Amination Reaction. Angew. Chem. Int. Ed. 2015, 54, 647-650.

65.     Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Mechanistic Insights into the Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Multisubstituted Pyrroles: Understanding the Remarkable Regio- and Enantioselectivity. J. Am. Chem. Soc. 2014, 136, 16251-16259.

66.     Xu, R.-Q.; Gu, Q.; Wu, W.-T.; Zhao, Z.-A.; You, S.-L.* Construction of Erythrinane Skeleton via Pd(0)-Catalyzed Intramolecular Dearomatization of para-Aminophenols J. Am. Chem. Soc. 2014, 136, 15469-15472.

67.     Zheng, J.; You, S.-L.* Construction of Axial Chirality via Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes. Angew. Chem. Int. Ed. 2014, 53, 13244-13247.

68.     Zhuo, C.-X.; Zheng, C.; You, S.-L.* Transition-metal-catalyzed Asymmetric Allylic Dearomatization Reactions Acc. Chem. Res. 2014, 47, 2558-2573.

69.     Yang, Z.-P.; Wu, Q.-F.; You, S.-L.* Direct Asymmetric Dearomatization of Pyridines and Pyrazines via Ir-Catalyzed Allylic Amination Reactions. Angew. Chem. Int. Ed. 2014, 53, 6986-6989.

70.     Zhuo, C.-X.; Zhou, Y.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of Poly-Substituted 2H-Pyrroles via Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Pyrroles J. Am. Chem. Soc. 2014, 136, 6590-6593 (selected as JACS Spotlights).

71.     Gao, D.-W.; Yin, Q.; Gu, Q.*; You, S.-L.* Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd(0)-Catalyzed Intramolecular Direct C-H Bond Arylation J. Am. Chem. Soc. 2014, 136, 4841-4844.

72.     Li, W.; Liu, C.; Zhang, H.; Ye, K.; Zhang, G.; Zhang, W.; Duan, Z.; You, S.*; Lei, A.* Palladium-Catalyzed Oxidative C-H/N-H Carbonylation for the Synthesis of β-lactams. Angew. Chem. Int. Ed. 2014, 53, 2443-2446.

73.     Wang, S.-G.; You, S.-L.* Cascade Hydrogenative Dearomatization of Pyridine and Asymmetric aza-Friedel-Crafts Alkylation Reaction. Angew. Chem. Int. Ed. 2014, 53, 2194-2197.

74.     Zhang, X.; Han, L.; You, S.-L.* Ir-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Indoles. Chem. Sci. 2014, 5, 1059-1063.

75.     Zhuo, C.-X.; You, S.-L.* Palladium-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Naphthol Derivatives. Angew. Chem. Int. Ed. 2013, 52, 10056-10059.

76.     Zhang, X.; Yang, Z.-P.; Liu, C.; You, S.-L.* Ru-Catalyzed Intermolecular Dearomatization Reaction of Indoles with Allylic Alcohols. Chem. Sci. 2013, 4, 3239-3243.

77.     Zhuo, C.-X.; Wu, Q.-F.; Zhao, Q.; Xu, Q.-L.; You, S.-L.* Enantioselective Functionalization of Indoles and Pyrroles via An in-situ Formed Spiro-intermediate J. Am. Chem. Soc. 2013, 135, 8169-8172.

78.     Gao, D.-W.; Shi, Y.-C.; Gu, Q.*; Zhao, Z.-L.; You, S.-L.* Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-catalyzed Direct Coupling with Aryl Boronic Acids J. Am. Chem. Soc. 2013, 135, 86-89.

79.     Xu, Q.-L.; Dai, L.-X.; You, S.-L.* Diversity Oriented Synthesis of Indole-based Peri-annulated Compounds via Allylic Alkylation Reactions. Chem. Sci. 2013, 4, 97-102.

80.     Zhuo, C.-X.; Zhang, W.*; You, S.-L.* Catalytic Asymmetric Dearomatization Reactions. Angew. Chem. Int. Ed. 2012, 51, 12662-12686.

81.     Liu, W.-B.; Zhang, X.; Dai, L.-X.; You, S.-L.* Asymmetric N-Allylation of Indoles via Ir-Catalyzed Allylic Alkylation of Indolines and Oxidation Strategy. Angew. Chem. Int. Ed. 2012, 51, 5183-5187.

82.     Liu, W.-B.; Zheng, C.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Ir-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies J. Am. Chem. Soc. 2012, 134, 4812-4821.

83.     Zheng, C.; You, S.-L.* Transfer Hydrogenation with Hantzsch Esters and Related Organic Hydride Donors Chem. Soc. Rev. 2012, 41, 2498-2518. (invited paper)

84.     Wu, Q.-F.; Zheng, C.; You, S.-L.* Enantioselective Syntheses of Spiro Cyclopentane-1,3'-indoles and 2,3,4,9-Tetrahydro-1H-carbazoles via Ir-Catalyzed Allylic Dearomatization and Stereospecific Migration. Angew. Chem. Int. Ed. 2012, 51, 1680-1683.

85.     Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L.* Asymmetric Dearomatization of Pyrroles via Ir-Catalyzed Allylic Substitution Reaction: Enantioselective Synthesis of Spiro-2H-pyrroles. Chem. Sci. 2012, 3, 205-208.

86.     Ye, K.-Y.; He, H.; Liu, W.-B.; Helmchen, G.; Dai, L-X.; You, S.-L.* Iridium-Catalyzed Allylic Vinylation and Asymmetric Allylic Amination Reactions with ortho-Aminostyrenes J. Am. Chem. Soc. 2011, 133, 19006-19014.

87.     Cai, Q.; Zheng, C.; Zhang, J.-W.; You, S.-L.* Enantioselective Michael-Mannich Polycyclization Cascade of Indolyl Enones by Quinine-Derived Primary Amine Angew. Chem. Int. Ed. 2011, 50, 8665-8669.

88.     Gu, Q.; You, S.-L.* Desymmetrization of Cyclohexadienones via Cinchonine Derived Thiourea-Catalyzed Enantioselective Aza-Michael Reaction and Total Synthesis of (-)-Mesembrine. Chem. Sci. 2011, 2, 1519-1522.

89.     Yin, Q.; You, S.-L.* Chiral Phosphoric Acid-Catalysed Friedel-Crafts Alkylation Reaction of Indoles with Racemic Spiro Indolin-3-ones. Chem. Sci. 2011, 2, 1344-1348.

90.     Wu, Q.-F.; Liu, W.-B.; Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.; You, S.-L.* Ir-Catalyzed Intramolecular Asymmetric Allylic Dearomatization of Phenols. Angew. Chem. Int. Ed. 2011, 50, 4455-4458.

91.     Cai, Q.; Zheng, C.; You, S.-L.* Enantioselective Intramolecular Aza-Michael Addition of Indoles Catalyzed by Chiral Phosphoric Acid. Angew. Chem. Int. Ed. 2010, 49, 8666-8669.

92.     Wu, Q.-F.; He, H.; Liu, W.-B.; You, S.-L.* Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation Reactions J. Am. Chem. Soc. 2010, 132, 11418-11419.

93.     Peng, H. M.; Dai, L.-X.; You, S.-L.* Enantioselective Palladium-Catalyzed Direct Alkylation and Olefination Reaction of Simple Arenes Angew. Chem. Int. Ed. 2010, 49, 5826-5828. (Highlights)

94.     Gu, Q.; Rong, Z.-Q.; Zheng, C.; You, S.-L.* Desymmetrization of Cyclohexadienones via Br?nsted Acid-Catalyzed Enantioselective Oxo-Michael Reaction J. Am. Chem. Soc. 2010, 132, 4056-4057.

95.     He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of 2,3-Dihydro-1H-benzo[b]azepines via Ir-Catalyzed Tandem Allylic Vinylation/Amination Reaction. Angew. Chem. Int. Ed. 2010, 49, 1496-1499.

96.     Cai, Q.; Zhao, Z.-A.; You, S.-L.* Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/ Intramolecular Friedel-Crafts Alkylation under Sequential Catalysis. Angew. Chem. Int. Ed. 2009, 48, 7428-7431.

97.     He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L.* Ir-Catalyzed Cross-Coupling of Styrene Derivatives with Allylic Carbonates: Free Amine Assisted Vinyl C-H Bond Activation J. Am. Chem. Soc. 2009, 131, 8346-8347.

98.     You, S.-L.*; Cai, Q.; Zeng, M. Chiral Br?nsted Acids Catalyzed Friedel-Crafts Alkylation Reaction Chem. Soc. Rev. 2009, 38, 2190-2201.

99.     Kang, Q.; Zhao, Z.-A.; You, S.-L.* Highly Enantioselective Friedel-Crafts Reaction of Indoles with Imines by a Chiral Phosphoric Acid. J. Am. Chem. Soc. 2007, 129, 1484-1485.

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